Silo Pharma announced that it has achieved positive results for its toxicology study of SP-26, a time-released and dosage controlled formulation of ketamine to treat fibromyalgia.  

In collaboration with Experimur, a Chicago-based toxicology testing and research laboratory, Silo Pharma tested SP-26 in a toxicology and tolerability study in minipigs using an ascending (descending) dosing regimen. The study utilized the bioanalytical methods required to perform toxicology studies by the FDA in advance of initiating clinical studies for SP-26. Here’s more: https://www.globenewswire.com/news-release/2023/03/15/2627698/0/en/Silo-Pharma-Announces-Positive-Results-from-IND-Enabling-Study-of-SP-26-for-Fibromyalgia.html

Can psilocybin treat neuropsychiatric Lyme disease? A new case study described an immunocompetent male with serologically positive neuropsychiatric Lyme disease who did not tolerate antimicrobial or psychotropic medications, but whose symptoms remitted when he began psilocybin in microdose (sub-hallucinogenic) amounts. Check it out: https://www.tandfonline.com/doi/full/10.2147/IMCRJ.S395342

Texas lawmakers filed a series of new bills aimed at promoting and expanding psychedelics research in the state.

The Lone Star State took some by surprise last session after the legislature enacted a measure to study the therapeutic benefits of psychedelics, and now more legislators are hoping to build on that momentum.

Three lawmakers in the state recently introduced separate reform proposals, including one that would expand the law that Gov. Greg Abbott allowed to take effect without his signature in 2021. The other two bills would create entirely new psychedelics-focused government bodies in the state to facilitate studies. For an overview of these newly-filed measures, click here: https://www.marijuanamoment.net/texas-lawmakers-file-three-bills-to-expand-state-sponsored-psychedelics-research/

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Did you know that the psychedelic substance Diisopropyltryptamine (DiPT) produces primarily auditory hallucinations?

According to Alexander Shulgin, at lower doses, the effects are similar to a flanging or a phase shift. At medium and higher dosages, the effect of DiPT is typically a radical shift downward in perceived pitch.

People who have taken DiPT have also reported that when someone is speaking, some of the words are completely omitted from the conversation or switched around to create an entirely new context.

You can read more about the auditory adventures of DiPT here: https://psychedelicspotlight.com/dipt-is-the-psychedelic-for-your-ears/

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